Fig. 1

Representative RP-HPLC profile of the pooled filtered skin secretion of L. labyrinthicus. RP-HPLC profile of L. labyrinthicus skin secretion in a C18 monolithic column monitored at 214 nm. Numbers 1–16 represent the sixteen fractions manually collected for the antiviral screening; the arrow indicates the active fraction. Inset: superimposed individual chromatographic profiles of the filtered skin secretions from three individuals, under the same chromatographic conditions