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Fig. 2 | Journal of Venomous Animals and Toxins including Tropical Diseases

Fig. 2

From: Articular inflammation induced by an enzymatically-inactive Lys49 phospholipase A2: activation of endogenous phospholipases contributes to the pronociceptive effect

Fig. 2

Edema induced by MT-II in (a) tibio-tarsal and (b) femoral-tibial-patellar rat joints. MT-II (10 μg/articulation) was injected in 25 (tibio-tarsal articulation) or 50 μL (femoral-tibial-patellar articulation) of PBS (vehicle). The same volume of PBS was injected in the contralateral articulation. The increase in the articulation was determined by measuring the joint edema using a caliper at 0 (time before injections) or 1, 2, 4, 8 and 24 h after MT-II or PBS injection. Results are expressed as the percentage in the increase in joint thickness of MT-II group in relation to the PBS group. Each point represents the mean ± SEM of six animals. *p < 0.05, **p < 0.01 and ***p < 0.001 indicate statistically significant differences when compared with baseline (time 0)

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Journal of Venomous Animals and Toxins including Tropical Diseases

ISSN: 1678-9199

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