Fig. 2

LyeTx I b – FITC intravitreal penetrates the retina. a The retina layers without peptide. b Retina layer 2 h after intravitreal injection of LyeTx I b - FITC (2.89 μM). c 4 h after intravitreal injection. d 6 h after intravitreal injection. e 8 h after intravitreal injection. RPE- Retinal Pigment Epithelium, ONL- Outer nuclear layer, INL- Inner nuclear layer, GCL-Ganglion cell layer. Digital images were obtained using a microscope (Apotome.2, ZEISS, Germany) equipped for epifluorescence and a standard fluorescein filter with a 20× objective. FITC was excited at 490 nm and presented emission at 526 nm